Wang, et al Clinical Study: data on file awaiting publication date.

This clinical study (2017-2020) with mild DR patients was conducted at Bascom Palmer Eye Institute (U of Miami) and showed the following:

• Improvement in retinal tissue perfusion (RTP)
• Best responders were patients with folate-related polymorphisms

Liu, et al Clinical Study: Macrovascular Research (2020)

This clinical study (2017-2020) with mild DR patients was conducted at Bascom Palmer Eye Institute (U of Miami) and showed the following:

• Improvement in conjunctival microcirculation and microvascular markers
• Improvement in Best Corrected Visual Acuity (BCVA)
• Homocysteine (Hcy) and oxidative stress were reduced
• Best responders were patients with folate-related polymorphisms

Shi, et al Clinical Study: Eye and Vision (2020)

Much of the above clinical improvements were derived from addressing the underlying nutritional deficiencies that are common among many patients with retinal ischemia such as mild diabetic retinopathy.

• Role of Elevated Homocysteine (Hcy) in progressive eye disease
• Impact of genetic polymorphisms to progressive eye disease

Changes in vision for Diabetic Retinopathy patients can improve in as little as six Months as seen in the study conducted at Bascom Palmer Eye institute and in the AR practice of Dr Craig Brown (Eye Center of Fayetteville).

Patients showed improvement at both 3 months and 6 months as compared to the expected deterioration of sight over time. We feel that better eyesight can be expected after a perfusion of both retinal and conjunctival tissue with improved retinal blood flow over that time period.

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